The HCRN
PROVEN MODEL: Our network is based on proven organizational models of multi-center collaborative research.
Two models we studied are the Children’s Oncology Group (COG) and the Autism Treatment Network (ATN). The COG, comprised of over 200 member institutions, has, in the last 40 years, worked to improve the survival rates of childhood cancer from less than 10% to over 77%. And ATN is setting the gold standard for diagnosis, treatment, and care of autistic people in North America. We consulted with the leadership of both groups and adopted the best practices for supporting high-quality clinical studies.
HCRN Centers
Hospital
|
University
|
Role
|
Joined
|
---|---|---|---|
University of Utah
|
Data Coordinating Center
|
2006
|
|
Primary Children’s Hospital
|
University of Utah
|
Coordinating and Participating Center
|
2006
|
Sick Kids
|
University of Toronto
|
Participating Center
|
2006
|
Children’s of Alabama
|
University of Alabama
|
Participating Center
|
2006
|
Texas Children’s Hospital
|
Baylor School of Medicine
|
Participating Center
|
2007
|
Seattle Children’s Hospital
|
University of Washington
|
Participating Center
|
2009
|
St. Louis Children’s Hospital
|
Washington Universtity
|
Participating Center
|
2010
|
Children’s Hospital of Pittsburgh of UPMC
|
University of Pittsburgh
|
Participating Center
|
2010
|
Monroe Carell Jr. Children’s Hospital
|
Vanderbilt University
|
Partipcating Center
|
2013
|
BC Children’s Hospital
|
University of British Columbia
|
Participating Center
|
2013
|
Alberta Children’s Hospital
|
University of Calgary
|
Participating Center
|
2016
|
Children’s Hospital Colorado
|
University of Colorado
|
Participating Center
|
2016
|
Children’s Hospital of Los Angeles
|
University of Southern California
|
Participating Center
|
2016
|
Johns Hopkins Hospital
|
Johns Hopkins University
|
Participating Center
|
2016
|
Nationwide Children’s Hospital
|
Ohio State University
|
Participating Center
|
2016
|
Our model overcomes the obstacles of previous efforts to study the condition. The pilot HCRN organization will consist of a central data coordinating center, and four research centers at high-patient-volume pediatric hospitals in North America. Principal investigators at member institutions will each lead an important study that will hopefully yield results for improving hydrocephalus treatment. All centers will enroll eligible patients in all appropriate studies concurrently. Our model makes sure the studies are both adequately powered by sufficient sample sizes and appropriately staffed, while also ensuring data is collected quickly and professionally.